Table of contents

  • Brand Names
  • Drug Combinations
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Pregnancy and Lactation Implications
  • Contraindications
  • Adverse Reactions
  • Toxicological Effects
  • Genes that may be involved
  • Drug Interactions
  • Dosage
  • Pharmacokinetics and Pharmacodynamics

Brand Names


Austria: Candio-Hermal, Mycostatin; Belgium: Nilstat, Nystatine; Bulgaria: Fungostatin, Nystatin; Cyprus: Mycostatin, Restatin; Czech Republic: Fungicidin; Denmark: Mycostatin; Finland: Mycostatin; France: Mycostatine; Germany: Adiclair, Biofanal, Candida Lokalicid, Candio-Hermal, Lederlind, Ledernyst, Moronal, Mykundex, Nystatin; Greece: Mycostatin, Nystamysyn; Hungary: Nystatin; Ireland: Mycostatin; Italy: Mycostatin, Nistatin; Lithuania: Nystatin; Luxembourg: Candio-Hermal, Nilstat, Nystatine; Malta: Nystan; Netherlands: Nystatine; Poland: Nystatyna; Portugal: Mycostatin; Romania: Nistatina; Slovakia: Fungicidin, Nystatin; Spain: Mycostatin; Sweden: Mycostatin; UK: Nystan, Nystatin.

North America

Canada: Nyaderm, Nystatin; USA: Mycostatin, Nilstat, Nystatin, Nystop.

Latin America

Argentina: Candermil, Candidias, Dipni, Micostatin, Neostatin, Nistamed, Nistat, Nistatina; Brazil: Canditrat, Inofungin, Kandistat, Micostal, Micostalab, Micostatin, Neo Mistatin, Neostatin, Nicostat, Nidazolin, Nistagyn, Nistatin, Nistatina, Nistaval-Nistatina, Nistomic, Tricocet; Mexico: Aponistan V, Bistatin V, Micostatin, Nistan, Nistaquin, Nistatina.


Japan: Nystatin.

Drug combinations

Nystatin and Hydrocortisone

Nystatin and Metronidazole

Nystatin and Triamcinolone

Nystatin and Zinc Oxide

Nystatin, Chlorhexidine, and Dexamethasone

Nystatin, Clobetasol, and Neomycin

Nystatin, Dexamethasone, and Metronidazole

Nystatin, Dexamethasone, and Neomycin

Nystatin, Halcinonide, and Neomycin

Nystatin, Metronidazole, and Neomycin

Nystatin, Neomycin, and Polymyxin B

Nystatin, Betamethasone, Gentamicin, and Tolnaftate

Nystatin, Boric acid, Hydrocortisone, and Metronidazole

Nystatin, Gramicidin, Neomycin, and Triamcinolone

Nystatin, Neomycin, Nitrofurazone, and Retinol (Vitamin A)

Nystatin, Neomycin, Thiostrepton, and Triamcinolone

Nystatin, Dexamethasone, Lidocaine, Metronidazole, and Neomycin


Nystatin: C~47~H~75~NO~17~. Mw: 926.0949. (1) 20-[(3-amino-3,6-dideoxy-D-mannopyranosyl)oxy]-4,6,8,11,12,16,18,36-octahydroxy-35,37,38-trimethyl-2,14-dioxooxacyclooctatriaconta-21,23,25,27,31,33-hexaene-17-carboxylic acid. CAS-1400-61-9.

Pharmacologic Category

Antifungals; Polyenes. Skin and Mucous Membrane Agents. (ATC-Code: A07AA02; D01AA01; G01AA01).

Mechanism of action

Binds to sterols in fungal cell membrane, changing cell wall permeability allowing for leakage of cellular contents.

Therapeutic use

Treatment of susceptible cutaneous, mucocutaneous, and oral cavity fungal infections normally caused by Candida species.

Pregnancy and lactiation implications

Use with caution in pregnancy. Does not enter breast milk (not absorbed orally).

Unlabeled use


Hypersensitivity to nystatin or any component of the formulation.

Warnings and precautions



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