Table of contents

  • Brand Names
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Pregnancy and Lactation Implications
  • Contraindications
  • Warnings and Precautions
  • Adverse Reactions
  • Drug Interactions
  • Dosage
  • Pharmacokinetics and Pharmacodynamics
  • Special Considerations

Brand Names


Austria: Synagis; Belgium: Synagis; Bulgaria: Synagis; Cyprus: Synagis; Czech Republic: Synagis; Denmark: Synagis; Estonia: Synagis; Finland: Synagis; France: Synagis; Germany: Synagis; Greece: Synagis; Hungary: Synagis; Ireland: Synagis; Italy: Synagis; Latvia: Synagis; Lithuania: Synagis; Malta: Synagis; Netherlands: Synagis; Poland: Synagis; Portugal: Synagis; Romania: Synagis; Slovakia: Synagis; Slovenia: Synagis; Spain: Synagis; Sweden: Synagis; UK: Synagis.

North America

Canada: Synagis; USA: Synagis.

Latin America

Argentina: Synagis; Brazil: Synagis; Mexico: Synagis.


Japan: Synagis.

Drug combinations


Palivizumab: Immunoglobulin G~1~ (human-mouse monoclonal MEDI-493γ~1~-chain antirespiratory syncytial virus protein F), disulfide with human-mouse monoclonal MEDI-493κ~1~-chain, dimer. CAS-188039-54-5.

Pharmacologic Category

Antivirals; Monoclonal Antibodies. (ATC-Code: J06BB169).

Mechanism of action

Exhibits neutralizing and fusion-inhibitory activity against respiratory syncytial virus.

Therapeutic use

Prevention of serious lower respiratory tract disease caused by respiratory syncytial virus in infants and children.

Pregnancy and lactiation implications

Not for adult use. Reproduction studies not conducted.

Unlabeled use


History of severe prior reaction to palivizumab or any component of the formulation.

Warnings and precautions

Very rare cases of anaphylaxis observed, as well as rare cases of severe acute hypersensitivity reactions (use with caution after mild hypersensitivity reaction). Use with caution in history of bleeding disorders (including thrombocytopenia). For I.M. use only. Use caution in thrombocytopenia or any coagulation disorder.



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