Poly-L-Lactic Acid
- Atc Codes:G01AD01
- CAS Codes:33135-50-1
- PHARMGKB ID:33135-50-1
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Drug Interactions
- Dosage
Brand Names
North America
USA: Sculptra.
Drug combinations
Chemistry
Poly-L-Lactic Acid: [-OCH(CH~3~)CO-]~n~. Mw: approx. 40000-70000. CAS-33135-50-1.
Pharmacologic Category
Cosmetic Agent, Implant. (ATC-Code: G01AD01).
Mechanism of action
Increases dermal thickness by causing local reaction leading to increase in collagen deposits. Eventually degraded and undergoes resorption.
Therapeutic use
Other Miscellaneous Therapeutic Agents. Restoration and/or correction of facial lipoatrophy in HIV.
Pregnancy and lactiation implications
Safety for use during pregnancy or breast-feeding not established.
Unlabeled use
Contraindications
Hypersensitivity to poly-L-lactic acid or any component of the formulation.
Warnings and precautions
Photosensitivity. Use with caution in patients on anticoagulants or antiplatelet medications. Avoid I.V. injection (may lead to occlusion, infarction, or embolism). Not for use if skin inflammation or infection exists in or near treatment area. Avoid use with implants.