Rubella Virus Vaccine (Live)
- Atc Codes:J07BJ
Table of contents
- Brand Names
- Drug Combinations
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Caution and personalized dose adjustment in patients with the following genotypes
- Other genes that may be involved
- Drug Interactions
- Dosage
Brand Names
Europe
Bulgaria: Rudivax; France: Rudivax; Germany: Ervevax, Röteln-Impfstoff HDC Merieux; Greece: Rudivax; Poland: Ervevax, Rudivax; Spain: Rubeaten.
North America
USA: Meruvax II.
Latin America
Argentina: Rudivax.
Asia
Japan: Freeze-dried live attenuated rubella vaccine.
Drug combinations
Rubella, Measles, and Mumps Vaccines (Combined)
Rubella, Measles, Mumps, and Varicella Virus Vaccine
Chemistry
Pharmacologic Category
Serums, Toxoids, and Vaccines; Vaccines. (ATC-Code: J07BJ).
Mechanism of action
Promotes active immunity by inducing rubella hemagglutination-inhibiting antibodies.
Therapeutic use
Selective active immunization against rubella.
Pregnancy and lactiation implications
Measles, mumps, rubella vaccine is vaccine of choice if recipients are likely to be susceptible to measles or mumps as well as to rubella. Following vaccination in mother, rubella virus may be transmitted to nursing infant via breast milk. Enters breast milk (use with caution in nursing women).
Unlabeled use
Contraindications
Hypersensitivity to rubella vaccine or any component of the vaccine. History of anaphylactic reactions to neomycin. Individuals with blood dyscrasias, leukemia, lymphomas, or other malignant neoplasms affecting bone marrow or lymphatic systems. Concurrent immunosuppressive therapy (not including steroid replacement). Primary and acquired immunodeficiency states; family history of congenital or hereditary immunodeficiency. Active/untreated tuberculosis. Current febrile illness. Pregnancy.
Warnings and precautions
Anaphylactoid and/or hypersensitivity reactions might occur. Use extreme caution in immediate-type hypersensitivity reactions to eggs. Use with caution in thrombocytopenia and patients who develop thrombocytopenia after first dose (thrombocytopenia may worsen). Recent administration of immune globulins may interfere with immune response. Use contraindicated in severely immunocompromised patients (may have reduced response to vaccination). Patients with HIV infection, asymptomatic and not severely immunosuppressed, may be vaccinated. Patients with leukemia in remission and who have not received chemotherapy for at least 3 months may be vaccinated. Products may contain albumin, gelatin and neomycin. Recent administration of blood or blood products may interfere with immune response.