Table of contents

  • Brand Names
  • Chemistry
  • Pharmacologic Category
  • Therapeutic Use
  • Pregnancy and Lactation Implications
  • Contraindications
  • Warnings and Precautions
  • Adverse Reactions
  • Genes that may be involved
  • Drug Interactions
  • Dosage
  • Special Considerations

Brand Names


Bulgaria: GHRH; France: Stimu GH; Germany: GHRH; Italy: GHRH; Netherlands: GHRH; UK: GHRH.

Drug combinations


Sermorelin Acetate: C~149~H~246~N~44~O~42~S xC~2~H~4~O~2~ yH~2~O. (1) Somatoliberin (human pancreatic islet), 29-L-argininamide-30-de-L-glutamine-31-de-L-glutamine-32-deglycine-33-de-L-glutamic acid-34-de-L-serine-35-de-L-asparagine-36-de-L-glutamine-37-de-L-glutamic acid-38-de-L-arginine-39-deglycine-40-de-L-alanine-41-de-L-arginine-42-de-L-alanine-43-de-L-arginine-44-de-L-leucinamide-, acetate, hydrate; (2) Growth hormone-releasing factor (human)-(1-29)-peptide amide, acetate (salt), hydrate; (3) 29-L-Argininamide-30-de-L-glutamine-31-de-L-glutamine-32-deglycine-33-de-L-glutamic acid-34-de-L-serine-35-de-L-asparagine-36-de-L-glutamine-37-de-L-glutamic acid-38-de-L-arginine-39-deglycine-40-de-L-alanine-41-de-L-arginine-42-de-L-alanine-43-de-L-arginine-44-de-L-leucinamide growth hormone-releasing factor (human pancreatic islet), acetate (salt), hydrate. CAS-114466-38-5; CAS-86168-78-7 (sermorelin)(1989).

Pharmacologic Category

Hormones and Synthetic Substitutes; Somatotropin Agonists. Diagnostic Agents; Pituitary Function; GRF Analog. (ATC-Code: H01AC04; V04CD03).

Mechanism of action

Therapeutic use

Diagnostic agent for evaluation of ability of pituitary gland to secrete growth hormone. GRF test. GH stimulation.

Pregnancy and lactiation implications

Has been shown to produce minor variations in fetuses of animals. There are no adequate studies in pregnant women. Excretion in breast milk unknown (use caution).

Unlabeled use


Hypersensitivity to sermorelin acetate, mannitol, or any component of the formulation.

Warnings and precautions

Not used for diagnosis of acromegaly. Thyroid status should be evaluated prior to treatment.



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