Table of contents

  • Brand Names
  • Drug Combinations
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Contraindications
  • Warnings and Precautions
  • Adverse Reactions
  • Genes that may be involved
  • Drug Interactions
  • Dosage

Brand Names


France: Sporiline; Germany: Tinatox, Tonoftal; Hungary: Chinofungin, Digifungin; Ireland: Mycil Athlete’s Foot, Tinaderm; Luxembourg: Sorgoa; Malta: Scholl Athlete’s Foot; Portugal: Tinaderme, Tolnaftato; UK: Scholl Athlete’s Foot.

North America

Canada: Absorbine Jr Antifungal Liquid, Avon Foot Works Therapeutic Antifungal Foot Cream, Dr. Scholl’s Athlete’s Foot Powder, Flexitol Medicated Foot Cream, Fungicure, Odor-Eaters Foot & Sneaker Spray, Pitrex, Proclearz Antifungal, Tinactin, Tolnaftate Antifungal, Zeasorb; USA: Blis-To-Sol, Fungi-Guard, Gold Bond Antifungal, Mycocide NS, Podactin, Q-Naftate, Tinactin Antifungal, Tinaderm, Ting Cream.

Latin America

Mexico: Excelsior Mic, Tinoxal, Tolnaftato.


Japan: Hi-Alarzin, Separin.

Drug combinations

Tolnaftate and Chlorhexidine Gluconate

Tolnaftate, Betamethasone, Gentamicin, and Nystatin


Tolnaftate: C~19~H~17~NOS. Mw: 307.41. (1) Carbamothioic acid, methyl(3-methylphenyl)-, O-2-naphthalenyl ester; (2) O-2-Naphthyl m,N-dimethylthiocarbanilate. CAS-2398-96-1 (1963).

Pharmacologic Category

Skin and Mucous Membrane Agents; Antifungals; Thiocarbamates. Topical Antifungal Agent. (ATC-Code: D01AE18).

Mechanism of action

Distorts hyphae and stunts mycelial growth in susceptible fungi.

Therapeutic use

Treatment of tinea pedis, tinea cruris, tinea corporis.

Pregnancy and lactiation implications

Unlabeled use


Hypersensitivity to tolnaftate or any component of the formulation. Nail and scalp infections.

Warnings and precautions

Discontinue if sensitivity or irritation occurs. Not for self-medication in children <2 years of age. For topical use only.



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